There is a well-known analogy, called a “String of Pearls,” that has gained recognition within the biotech/pharma industry. It was initially introduced by a respected leader in the industry to signify a strategic management concept of focusing upon an enterprise’s clearly defined areas of therapeutic strength and then strategically deciding upon which acquisition opportunities to pursue within those confines. We use the term to describe our technology platform – a coherent “string” upon which a series of curative vaccines, or “pearls,” are connected. Each pearl is strikingly similar, but at the same time, uniquely applicable to its own therapeutic indication within the scope of inflammatory autoimmune and neurodegenerative disease.
The TregTherapeutics technology platform is truly transformative in its simplicity, its elegance, and its universal application. The platform is based on an underlying mechanism of action that is a common denominator among all inflammatory diseases. The premise is that, built upon this platform, unique tolerogenic vaccines for specific diseases can be designed to eliminate the pathological immune response associated with them and to restore homeostasis. …Healing and restoration. Furthermore, this can be accomplished without global immunological compromise. TregTherapeutics is, thus, a purveyor of pearls, each a cure for a particular disease, strung upon the commonality of the science – a thing of beauty and a foundation for the dream that will free so many people from the scourge of chronic inflammatory disease. Yes, this is transformative, holding forth the promise of changing the world for millions of patients suffering from these devastating diseases.
We started with multiple sclerosis, have progressed into celiac disease, and further afield still with ALS. All in a coordinated strategy to move these vital therapeutic resources into clinical reality. Profound implications, pearl by pearl. .
This technology platform contains the secret for accomplishing so much for mankind. Elegant design and function linked together in a string of pearls that will change the world. A simple concept – a simple vaccine – a worthwhile enterprise – orchestrating human response to disease.